Description

1-Cyclopentyl-7-Cyclopropyl-2-Mercapto-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition or other specific biological pathways.
• Drug Discovery & Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization due to its unique pyridopyrimidine core.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Custom Synthesis: Acts as a starting material for the custom synthesis of specialized derivatives and analogs for proprietary research programs.

Basic Information

Product Name	1-Cyclopentyl-7-Cyclopropyl-2-Mercapto-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid
CAS No.	937599-78-5
Molecular Formula	C17H17N3O3S
Molecular Weight	343.40 g/mol
Synonyms	1-Cyclopentyl-7-cyclopropyl-2-mercapto-4-oxo-1,4-dihydro-5-pyrido[2,3-d]pyrimidinecarboxylic acid; 5-Pyrido[2,3-d]pyrimidinecarboxylic acid, 1,4-dihydro-1-cyclopentyl-7-cyclopropyl-2-mercapto-4-oxo-; 937599-78-5; Cyclopentyl-cyclopropyl-mercapto-oxo-dihydropyridopyrimidinecarboxylic acid; CAS 937599-78-5
EINECS	Contact for details

Quality Control

Our production of 1-Cyclopentyl-7-Cyclopropyl-2-Mercapto-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid adheres to stringent quality protocols suitable for pharmaceutical intermediate applications. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with client specifications and industry standards. Comprehensive Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.