Description

2-Mercapto-7-Methyl-4-Oxo-1-(Tetrahydrofuran-2-Ylmethyl)-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and antiviral treatments. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates targeting specific enzymatic pathways.
• Oncology Research: Used in the development of potential kinase inhibitors and other targeted cancer therapies due to its dihydropyrido[2,3-d]pyrimidine core.
• Antiviral Agent Development: Serves as a precursor in the research of compounds with potential activity against viral polymerases or proteases.
• Chemical Biology & Proteomics: Employed as a tool compound or a scaffold for creating chemical probes to study protein function and disease mechanisms.
• Process Chemistry & Scale-Up: Utilized by process chemists for route scouting, optimization, and the pilot-scale production of advanced intermediates.
• Custom Synthesis: A starting material for the custom synthesis of more complex, tailored molecules for specific client research programs.

Basic Information

Item	Details
Product Name	2-Mercapto-7-Methyl-4-Oxo-1-(Tetrahydrofuran-2-Ylmethyl)-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid
CAS No.	937599-74-1
Molecular Formula	C16H17N3O4S
Molecular Weight	347.39 g/mol
Synonyms	1,4-Dihydro-2-mercapto-7-methyl-4-oxo-1-[(tetrahydro-2-furanyl)methyl]pyrido[2,3-d]pyrimidine-5-carboxylic acid; 1-(Tetrahydrofuran-2-ylmethyl)-2-mercapto-7-methyl-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidine-5-carboxylic acid; 937599-74-1; Pyrido[2,3-d]pyrimidine-5-carboxylic acid, 1,4-dihydro-2-mercapto-7-methyl-4-oxo-1-[(tetrahydro-2-furanyl)methyl]-; THF-substituted dihydropyridopyrimidine carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Mercapto-7-Methyl-4-Oxo-1-(Tetrahydrofuran-2-Ylmethyl)-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container to maximize shelf-life stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.