Description

1-(2,5-Dimethylphenyl)-2-Mercapto-7-Methyl-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on oncology, antiviral, and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel pyridopyrimidine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Oncology Drug Development: Serves as a core scaffold for potential kinase inhibitors and other targeted cancer therapies.
• Antiviral Agent Synthesis: Employed in the research and development of antiviral compounds.
• Biochemical Research: Used as a tool compound to study specific enzymatic pathways and biological targets.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules for clinical trials.

Basic Information

Product Name	1-(2,5-Dimethylphenyl)-2-Mercapto-7-Methyl-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid
CAS No.	937599-72-9
Molecular Formula	C18H15N3O3S
Molecular Weight	353.40 g/mol
Synonyms	1-(2,5-Dimethylphenyl)-2-mercapto-7-methyl-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidine-5-carboxylic acid; 7-Methyl-1-(2,5-dimethylphenyl)-2-sulfanylidene-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidine-5-carboxylic acid; Pyrido[2,3-d]pyrimidine-5-carboxylic acid, 1,4-dihydro-1-(2,5-dimethylphenyl)-7-methyl-4-oxo-2-mercapto-; CAS 937599-72-9
EINECS	Contact for details

Quality Control

Our 1-(2,5-Dimethylphenyl)-2-Mercapto-7-Methyl-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container to minimize degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.