Description

3-Fluoro-4-(2,2,2-trifluoroethoxy)aniline is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoroethoxy substituent, makes it an essential intermediate for creating compounds with enhanced biological activity and specific physicochemical properties. This compound is primarily required by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved metabolic stability and membrane permeability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), enhancing charge transport and thermal stability.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique surface properties, chemical resistance, and low dielectric constants.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating libraries of fluorinated compounds for screening.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments that offer superior lightfastness and color properties.

Basic Information

Item	Details
Product Name	3-Fluoro-4-(2,2,2-trifluoroethoxy)aniline
CAS No.	937598-57-7
Molecular Formula	C8H7F4NO
Molecular Weight	209.14 g/mol
Synonyms	3-Fluoro-4-(2,2,2-trifluoroethoxy)benzenamine; 4-Amino-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene; 1-Fluoro-2-(2,2,2-trifluoroethoxy)-4-aminobenzene; 3-Fluoro-4-(trifluoroethoxy)aniline; 3-Fluoro-4-(2,2,2-trifluoroethoxy)phenylamine; 937598-57-7; FC-937598-57-7
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-(2,2,2-trifluoroethoxy)aniline is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.