Description

4-(Pyrimidin-5-Ylethynyl)Benzaldehyde (Saltdata: Free) is a high-purity organic building block featuring a benzaldehyde core linked to a pyrimidine ring via an ethynyl bridge. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, particularly in the construction of complex heterocyclic systems and functional materials. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its heterocyclic structure.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in Sonogashira coupling and other palladium-catalyzed reactions to build conjugated molecular architectures.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in organic chemistry.

Basic Information

Product Name	4-(Pyrimidin-5-Ylethynyl)Benzaldehyde (Saltdata: Free)
CAS No.	936940-81-7
Molecular Formula	C₁₃H₈N₂O
Molecular Weight	208.22 g/mol
Synonyms	5-[(4-Formylphenyl)ethynyl]pyrimidine; 4-[(Pyrimidin-5-yl)ethynyl]benzaldehyde; 4-(Pyrimidin-5-ylethynyl)benzaldehyde; Benzaldehyde, 4-[(5-pyrimidinyl)ethynyl]-; 936940-81-7; 4-(Pyrimidin-5-Ylethynyl)Benzaldehyde Free Base
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.