Description

1-Piperazinecarboxylic Acid, 4-[6-[(5-Ethenyl-2-Thiazolyl)Amino]-2-Methyl-4-Pyrimidinyl]-, 1,1-Dimethylethyl Ester is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Probe Development: Serves as a core structure for creating tools to study specific biological pathways and targets.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific API (Active Pharmaceutical Ingredient) development projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and drug discovery initiatives.
• Pre-clinical Development: Employed in the synthesis of compounds for pharmacological and toxicological evaluation.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-[6-[(5-Ethenyl-2-Thiazolyl)Amino]-2-Methyl-4-Pyrimidinyl]-, 1,1-Dimethylethyl Ester
CAS No.	936845-86-2
Molecular Formula	C19H26N6O2S
Molecular Weight	402.52 g/mol
Synonyms	tert-Butyl 4-(6-((5-vinylthiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazine-1-carboxylate; 4-[6-[(5-Ethenyl-2-Thiazolyl)Amino]-2-Methyl-4-Pyrimidinyl]-1-Piperazinecarboxylic Acid 1,1-Dimethylethyl Ester; BOC-Piperazine-Vinylthiazolylaminopyrimidine Derivative; (tert-Butoxycarbonyl)-4-(6-((5-vinylthiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazine; 936845-86-2; UNII-7K5F8VL8QN
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylic Acid, 4-[6-[(5-Ethenyl-2-Thiazolyl)Amino]-2-Methyl-4-Pyrimidinyl]-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.