Description

1-(6-Chloro-2-Methylpyrimidin-4-Yl)-4-Hydroxypiperidine is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesis and scale-up projects.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization in medicinal chemistry and material science.
• Academic & Contract Research: Essential for exploratory research in universities and contract research organizations (CROs) focusing on novel heterocyclic compounds.
• Process Chemistry: Employed in route scouting and optimization studies for the commercial-scale manufacturing of APIs.

Basic Information

Product Name	1-(6-Chloro-2-Methylpyrimidin-4-Yl)-4-Hydroxypiperidine
CAS No.	936845-82-8
Molecular Formula	C10H14ClN3O
Molecular Weight	227.69 g/mol
Synonyms	4-Hydroxy-1-(6-chloro-2-methyl-4-pyrimidinyl)piperidine; 1-(6-Chloro-2-methylpyrimidin-4-yl)piperidin-4-ol; 4-Piperidinol, 1-(6-chloro-2-methyl-4-pyrimidinyl)-; 936845-82-8; 6-Chloro-2-methyl-4-(4-hydroxypiperidin-1-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our 1-(6-Chloro-2-Methylpyrimidin-4-Yl)-4-Hydroxypiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.