Description

2-(Chloromethyl)Pyrimidine Hydrochloride is a versatile and reactive chemical building block, primarily used as a key intermediate in organic synthesis. Its value lies in the chloromethyl and pyrimidine functionalities, which allow for efficient derivatization and incorporation into more complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, especially those containing pyrimidine cores, such as kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the pyrimidine moiety is a key structural component.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential use as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Bioconjugation: The reactive chloromethyl group can be utilized for labeling or modifying biomolecules in biochemical research.

Basic Information

Product Name	2-(Chloromethyl)Pyrimidine Hydrochloride
CAS No.	936643-80-0
Molecular Formula	C5H6Cl2N2
Molecular Weight	165.02 g/mol
Synonyms	Pyrimidine, 2-(chloromethyl)-, hydrochloride (1:1); 2-(Chloromethyl)pyrimidine HCl; 2-(Chloromethyl)pyrimidine monohydrochloride; (Chloromethyl)pyrimidine hydrochloride; 2-Pyrimidinylmethyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)Pyrimidine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous demands of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.