Description

3-(4-Aminophenyl)-6-Fluoro-7-(Methylamino)Quinazoline-2,4(1H,3H)-Dione is a high-purity, functionalized quinazoline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate for the synthesis of novel, targeted therapeutic agents. It is primarily utilized by research institutions, CROs/CDMOs, and pharmaceutical companies engaged in the discovery of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology Probe: Used in biochemical assays to study enzyme function and signal transduction pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API manufacturing.
• Preclinical Development: Utilized in the production of candidate compounds for pharmacological and toxicological evaluation.

Basic Information

Product Name	3-(4-Aminophenyl)-6-Fluoro-7-(Methylamino)Quinazoline-2,4(1H,3H)-Dione
CAS No.	936501-00-7
Molecular Formula	C16H13FN4O2
Molecular Weight	312.30 g/mol
Synonyms	6-Fluoro-7-(methylamino)-3-(4-aminophenyl)quinazoline-2,4(1H,3H)-dione; 3-(4-Aminophenyl)-6-fluoro-7-(methylamino)-1H,3H-quinazoline-2,4-dione; 936501-00-7; 7-(Methylamino)-6-fluoro-3-(4-aminophenyl)-1,3-dihydro-2,4-quinazolinedione; 6-Fluoro-7-methylamino-3-(4-aminophenyl)quinazoline-2,4-dione; 3-(4-Aminophenyl)-6-fluoro-7-methylaminoquinazoline-2,4-dione
EINECS	Contact for details

Quality Control

Our 3-(4-Aminophenyl)-6-Fluoro-7-(Methylamino)Quinazoline-2,4(1H,3H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC purity analysis and structural confirmation (NMR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.