Description

Ne-Methanesulfonyl-L-Lysine is a high-purity, protected amino acid derivative designed for advanced chemical synthesis. This compound is a critical building block in the development of novel peptides and pharmaceutical intermediates, offering precise control over molecular structure. It is essential for research and production in pharmaceutical development, biotechnology, and fine chemical manufacturing where high-fidelity lysine modification is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Peptide Synthesis: Serves as a protected lysine derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation Chemistry: Used for site-specific modification of proteins and antibodies in biopharmaceutical development.
• Chemical Biology Research: A valuable tool compound for studying enzyme mechanisms and protein-protein interactions.
• Proteomics & Biomarker Discovery: Employed in the preparation of affinity probes and isotopic labeling reagents.
• Fine Chemical Synthesis: Building block for creating complex organic molecules with specific chiral centers.

Basic Information

Product Name	Ne-Methanesulfonyl-L-Lysine
CAS No.	936030-49-8
Molecular Formula	C7H16N2O4S
Molecular Weight	224.28 g/mol
Synonyms	N(epsilon)-Methanesulfonyl-L-lysine; L-Lysine, N6-(methylsulfonyl)-; N6-Methanesulfonyl-L-lysine; (2S)-2-Amino-6-(methylsulfonylamino)hexanoic acid; Nε-Methanesulfonyl-L-lysine; Ms-Lys-OH; Methanesulfonyl protected lysine; Protected L-lysine derivative
EINECS	Contact for details

Quality Control

Our Ne-Methanesulfonyl-L-Lysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Contact for details
Chiral Purity (HPLC)	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.