Description

5-Bromo-4-(Trifluoromethyl)Pyrimidin-2-Amine is a high-value, multi-functional pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and trifluoromethyl substituents, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science Precursor: Serves as a building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and labeling reagents for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-4-(Trifluoromethyl)Pyrimidin-2-Amine
CAS No.	935534-47-7
Molecular Formula	C5H3BrF3N3
Molecular Weight	241.99 g/mol
Synonyms	2-Amino-5-bromo-4-(trifluoromethyl)pyrimidine; 5-Bromo-4-(trifluoromethyl)-2-pyrimidinamine; 4-(Trifluoromethyl)-5-bromopyrimidin-2-amine; 935534-47-7; 5-Bromo-4-trifluoromethylpyrimidin-2-ylamine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-(Trifluoromethyl)Pyrimidin-2-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and we support customer audits and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.