Description

5-Fluoro-2-Methoxybenzenesulfonylfluoride is a specialized organosulfur compound featuring both methoxy and sulfonyl fluoride functional groups. This chemical serves as a versatile and reactive building block, primarily valued for its role in synthesizing more complex molecules in advanced research and development. It is particularly essential for pharmaceutical chemists and agrochemical researchers engaged in creating novel active ingredients, where its unique structure enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, contributing to the development of next-generation crop protection agents.
• Chemical Biology & Proteomics: Employed as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent inhibitors due to the electrophilic sulfonyl fluoride moiety.
• Material Science Research: Investigated as a monomer or cross-linking agent in the synthesis of specialty polymers with unique surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in bespoke synthesis projects for clients.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental studies in organic synthesis and reaction mechanism exploration.

Basic Information

Product Name	5-Fluoro-2-Methoxybenzenesulfonylfluoride
CAS No.	935534-28-4
Molecular Formula	C7H6F2O3S
Molecular Weight	220.18 g/mol
Synonyms	2-Methoxy-5-fluorobenzenesulfonyl fluoride; 5-Fluoro-2-methoxybenzene-1-sulfonyl fluoride; 1-Fluoro-4-methoxy-2-(fluorosulfonyl)benzene; 2-Fluoro-5-methoxybenzenesulfonyl fluoride; 935534-28-4; 5-Fluoro-2-methoxybenzenesulfonyl fluoride; Benzenesulfonyl fluoride, 5-fluoro-2-methoxy-
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-2-Methoxybenzenesulfonylfluoride is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.