Description

2,4-Dichloro-7-Tosyl-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value, multi-functional heterocyclic building block critical for advanced organic synthesis. This compound serves as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry & Scale-up: Serves as a critical building block during the development and optimization of scalable synthetic routes for API manufacturing.
• Agrochemical Research: Potential intermediate for developing novel herbicides or plant growth regulators, leveraging its dichloro-pyrimidine core.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and advanced intermediates.

Basic Information

Product Name	2,4-Dichloro-7-Tosyl-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	934524-10-4
Molecular Formula	C15H11Cl2N3O2S
Molecular Weight	368.24 g/mol
Synonyms	7H-Pyrrolo[2,3-d]pyrimidine, 2,4-dichloro-7-[(4-methylphenyl)sulfonyl]-; 2,4-Dichloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine; 2,4-Dichloro-7-(p-tolylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine; 2,4-Dichloro-7-tosylpyrrolo[2,3-d]pyrimidine; 934524-10-4; Pyrrolo[2,3-d]pyrimidine, 2,4-dichloro-7-[(4-methylphenyl)sulfonyl]-7H-
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-7-Tosyl-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) compliance for advanced intermediates, and we can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.