Description

Pyrido[2,3-D]Pyrimidin-7(8H)-One, 8-Ethyl-4-Methyl-2-(Methylsulfonyl)-6-Phenyl- is a high-value, heterocyclic organic compound belonging to the pyridopyrimidinone class. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, particularly for its role as a key building block in kinase inhibitor synthesis. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in vitro to study specific enzyme inhibition pathways and cellular signaling mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	Pyrido[2,3-D]Pyrimidin-7(8H)-One, 8-Ethyl-4-Methyl-2-(Methylsulfonyl)-6-Phenyl-
CAS No.	934496-69-2
Molecular Formula	C₁₇H₁₉N₃O₃S
Molecular Weight	345.42 g/mol
Synonyms	8-Ethyl-4-methyl-2-(methylsulfonyl)-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-one; 2-Methanesulfonyl-8-ethyl-4-methyl-6-phenyl-1,8-dihydropyrido[2,3-d]pyrimidin-7-one; 934496-69-2; 8-Ethyl-4-methyl-2-methylsulfonyl-6-phenyl-1H-pyrido[2,3-d]pyrimidin-7-one; Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-ethyl-4-methyl-2-(methylsulfonyl)-6-phenyl-; 6-Phenyl-8-ethyl-4-methyl-2-methylsulfonyl-pyrido[2,3-d]pyrimidin-7-one
EINECS	Contact for details

Quality Control

Our Pyrido[2,3-D]Pyrimidin-7(8H)-One intermediate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems support development toward cGMP standards for advanced pharmaceutical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with appropriate desiccant to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.