Description

6-(4-Methyl-1-Piperazinyl)-n-(5-Methyl-1H-Pyrazol-3-Yl)-2-[(1Z)-2-Phenylethenyl]-4-Pyrimidinamine is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in modern medicinal chemistry. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: Serves as a core scaffold for the research and development of potential kinase inhibitors.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying biological processes and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Product Name	6-(4-Methyl-1-Piperazinyl)-n-(5-Methyl-1H-Pyrazol-3-Yl)-2-[(1Z)-2-Phenylethenyl]-4-Pyrimidinamine
CAS No.	934353-77-2
Molecular Formula	C21H24N8
Molecular Weight	388.47 g/mol
Synonyms	6-(4-Methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(1Z)-2-phenylethenyl]pyrimidin-4-amine; 2-[(1Z)-2-Phenylethenyl]-6-(4-methyl-1-piperazinyl)-N-(5-methyl-1H-pyrazol-3-yl)-4-pyrimidinamine; 934353-77-2; UNII-9J8Q3K1V4I; 9J8Q3K1V4I; (Z)-6-(4-Methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-styrylpyrimidin-4-amine; 2-Styryl-6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 6-(4-Methyl-1-Piperazinyl)-n-(5-Methyl-1H-Pyrazol-3-Yl)-2-[(1Z)-2-Phenylethenyl]-4-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.