Description

4-Fluoro-3-Hydroxybenzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive benzylic alcohol and a phenolic hydroxyl group adjacent to a fluorine atom, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-inflammatory, and anti-infective applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers and cross-linkers in the manufacture of high-performance electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a functional monomer to introduce fluorine and hydroxyl groups into polymer backbones, improving chemical resistance, surface properties, and adhesion.
• Chemical Research & Development: A valuable reagent in academic and industrial labs for methodology development, catalysis studies, and exploring new fluorination chemistry pathways.
• Diagnostic Agent Precursor: Potential building block for synthesizing fluorinated contrast agents or probes used in medical imaging techniques like PET (Positron Emission Tomography).

Basic Information

Product Name	4-Fluoro-3-Hydroxybenzyl Alcohol
CAS No.	934241-78-8
Molecular Formula	C7H7FO2
Molecular Weight	142.13 g/mol
Synonyms	(3-Hydroxy-4-fluorophenyl)methanol; 4-Fluoro-3-hydroxybenzenemethanol; 3-Hydroxy-4-fluorobenzyl alcohol; 1-(Hydroxymethyl)-2-fluoro-5-hydroxybenzene; 2-Fluoro-5-(hydroxymethyl)phenol; 4-Fluoro-3-hydroxy benzyl alcohol; 3-Hydroxy-4-fluoro benzyl alcohol; F-HBA
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-3-Hydroxybenzyl Alcohol adheres to stringent in-process controls and final batch testing to ensure consistent high purity and reliable performance. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support development and scale-up projects with custom synthesis and analytical method development to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.