Description

Fmoc-Met-Oh-15N CAS NO 934183-50-3 is a stable isotope-labeled derivative of the amino acid methionine, specifically designed for advanced research and development in peptide synthesis and metabolic studies. This compound is critical for applications requiring high-purity, isotopically enriched building blocks to ensure accurate analytical results and reliable synthetic outcomes. It is primarily utilized by pharmaceutical researchers, biochemists, and contract research organizations (CROs) engaged in proteomics, mass spectrometry, and the development of novel peptide-based therapeutics.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a crucial, isotopically labeled Fmoc-protected amino acid building block for the automated synthesis of peptides.
• Metabolic Pathway Tracing: Used in 15N-labeling studies to investigate methionine metabolism, protein turnover, and sulfur amino acid pathways in biological systems.
• Mass Spectrometry Standards: Acts as an internal standard for the precise quantification of methionine-containing peptides and proteins in LC-MS and proteomic analyses.
• Biopharmaceutical Development: Employed in the research and development of peptide drugs, where isotopic labeling aids in pharmacokinetic and stability studies.
• NMR Spectroscopy: Provides a 15N-enriched probe for structural elucidation and dynamic studies of peptides and proteins using nuclear magnetic resonance.
• Academic & Industrial Research: Essential for basic biochemical research in universities and for applied R&D in biotechnology and pharmaceutical companies.

Basic Information

Product Name	Fmoc-Met-Oh-15N
CAS No.	934183-50-3
Molecular Formula	C20H2115NO4S
Molecular Weight	Contact for details
Synonyms	Fmoc-L-Methionine-15N; N-(9-Fluorenylmethoxycarbonyl)-L-methionine-15N; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4-(methylsulfanyl)butanoic-15N acid; Fmoc-Methionine-15N-OH; Fmoc-L-Met-15N-OH; Nα-Fmoc-L-methionine-15N; Fmoc-Met(15N)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-Met-Oh-15N is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity for sensitive research applications. Each batch is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and chiral purity is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment (15N)	≥98 atom %
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.