Description

Methyl 3-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazoline-7-Carboxylate is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in modern pharmaceutical research and development, particularly for the synthesis of novel therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of quinazolinone-based drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that leverage the quinazolinone scaffold.
• Organic Synthesis Building Block: Serves as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for screening.
• Material Science Research: Investigated as a potential component in the development of organic electronic materials and advanced polymers.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodological studies in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	Methyl 3-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazoline-7-Carboxylate
CAS No.	934050-55-2
Molecular Formula	C12H12N2O4
Molecular Weight	248.24 g/mol
Synonyms	7-Carbomethoxy-3-methyl-3,4-dihydro-2,4-quinazolinedione; Methyl 3-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylate; 3-Methyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid methyl ester; 7-Methoxycarbonyl-3-methyl-3,4-dihydroquinazoline-2,4-dione; Quinazoline-7-carboxylic acid, 1,2,3,4-tetrahydro-3-methyl-2,4-dioxo-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazoline-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.