Description

2-(4-Fluorophenyl)Pyrimidine-5-Carboxylic Acid is a high-purity fluorinated pyrimidine derivative, a critical building block in modern organic synthesis. This compound is valued for its role as a versatile intermediate in the development of advanced pharmaceutical and agrochemical active ingredients. It is primarily sought by research institutions and industrial manufacturers in the life sciences sector for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl-pyrimidine scaffold.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Bioconjugation & Probe Development: The carboxylic acid group enables coupling reactions for creating fluorescent probes or bioconjugates for diagnostic applications.

Basic Information

Product Name	2-(4-Fluorophenyl)Pyrimidine-5-Carboxylic Acid
CAS No.	933988-26-2
Molecular Formula	C11H7FN2O2
Molecular Weight	218.19 g/mol
Synonyms	5-Pyrimidinecarboxylic acid, 2-(4-fluorophenyl)-; 2-(p-Fluorophenyl)pyrimidine-5-carboxylic acid; 2-(4-Fluorophenyl)-5-pyrimidinecarboxylic acid; 933988-26-2; 4-Fluoro-2-pyrimidin-5-ylbenzoic acid (alternative); FPCA (abbreviation); 2-(4-Fluorophenyl)pyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.