Description

5-Fluoro-4-(2-Methyl-1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Imidazol-5-Yl)Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted therapeutic agents. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel drug candidates, especially in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Kinase Inhibitor Development: Serves as a core scaffold in the research and development of potent and selective kinase inhibitors.
• Oncology Drug Candidates: Integral component in the synthetic pathways for investigational anti-cancer compounds.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule synthesis.
• Biochemical Research: Used as a reference standard or probe in biochemical assays to study specific biological pathways.

Basic Information

Product Name	5-Fluoro-4-(2-Methyl-1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Imidazol-5-Yl)Pyrimidin-2-Amine
CAS No.	933784-97-5
Molecular Formula	C13H16FN5O
Molecular Weight	277.30 g/mol
Synonyms	5-Fluoro-4-[2-methyl-1-(oxan-4-yl)imidazol-5-yl]pyrimidin-2-amine; 2-Amino-5-fluoro-4-[2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl]pyrimidine; 933784-97-5; 5-Fluoro-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine; UNII-9J2Q9I3T4I; SCHEMBL23346895; AKOS040750623; FT-0773297.
EINECS	Contact for details

Quality Control

Our 5-Fluoro-4-(2-Methyl-1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Imidazol-5-Yl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound should be considered moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.