Description

Quinazoline-4-Carbaldehyde is a versatile and high-value heterocyclic building block, specifically a quinazoline derivative functionalized with an aldehyde group at the 4-position. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its reactive aldehyde moiety, which serves as a key handle for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various pharmacologically active quinazoline derivatives, including kinase inhibitors and anticancer agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides that leverage the quinazoline scaffold for bioactivity.
• Organic Synthesis Building Block: The reactive aldehyde group enables condensation, reductive amination, and other key reactions to create diverse chemical libraries for screening.
• Material Science Precursor: Serves as a starting material for synthesizing organic ligands, dyes, and photoactive compounds.
• Academic & Contract Research: Essential for fundamental research in medicinal chemistry and heterocyclic compound development.

Basic Information

Item	Details
Product Name	Quinazoline-4-Carbaldehyde
CAS No.	933747-26-3
Molecular Formula	C9H6N2O
Molecular Weight	158.16 g/mol
Synonyms	4-Formylquinazoline; Quinazoline-4-carboxaldehyde; 4-Quinazolinecarboxaldehyde; 4-Quinazolinecarbaldehyde; 4-Carbaldehydequinazoline; 4-Quinazoline aldehyde; 4-Aldehydequinazoline; Quinazoline-4-aldehyde
EINECS	Contact for details

Quality Control

Our Quinazoline-4-Carbaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with the standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.