Description

6-Fluoro-1H-Indole-2-Carbaldehyde is a high-purity fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of both fluorine and an aldehyde functional group onto the indole scaffold, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in developing new pesticides and herbicides where the fluorinated indole structure contributes to biological activity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers and organic electronic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, due to its reactive aldehyde group.
• Bioconjugation: The aldehyde functionality allows for site-specific labeling and conjugation of biomolecules in diagnostic probe development.
• Academic & R&D: A valuable reagent for exploring new synthetic methodologies and structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	6-Fluoro-1H-Indole-2-Carbaldehyde
CAS No.	933746-81-7
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	6-Fluoro-1H-indole-2-carboxaldehyde; 6-Fluoroindole-2-carbaldehyde; 2-Formyl-6-fluoroindole; 6-Fluoro-2-indolecarboxaldehyde; 6-Fluoro-2-formylindole; 6-Fluoro-1H-indole-2-carboxaldehyde; 933746-81-7; 6-Fluoroindole-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 6-Fluoro-1H-Indole-2-Carbaldehyde is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.