Description

2-Chloro-5-Methylpyrimidine-4-Carboxylic Acid is a high-purity pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial labs.
• Material Science: Potential building block for functionalized polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and pilot-scale batches.

Basic Information

Product Name	2-Chloro-5-Methylpyrimidine-4-Carboxylic Acid
CAS No.	933746-10-2
Molecular Formula	C7H5ClN2O2
Molecular Weight	184.58 g/mol
Synonyms	4-Pyrimidinecarboxylic acid, 2-chloro-5-methyl-; 2-Chloro-5-methyl-4-pyrimidinecarboxylic acid; 2-Chloro-5-methylpyrimidine-4-carboxylic acid; 933746-10-2; 5-Methyl-2-chloropyrimidine-4-carboxylic acid; 2-Chloro-5-methyl-1,3-diazine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Methylpyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for all shipments, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.