Description

5-Bromo-4-Methyl-2-Pyrimidinecarboxylic Acid is a high-purity pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular modifications. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific pyrimidine scaffolds.
• Chemical Research: Serves as a versatile building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Material Science: Potential precursor for the synthesis of functionalized organic materials and ligands for metal-organic frameworks (MOFs).
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	5-Bromo-4-Methyl-2-Pyrimidinecarboxylic Acid
CAS No.	933745-86-9
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	5-Bromo-4-methylpyrimidine-2-carboxylic acid; 4-Methyl-5-bromopyrimidine-2-carboxylic acid; 2-Pyrimidinecarboxylic acid, 5-bromo-4-methyl-; 5-Bromo-4-methyl-2-carboxypyrimidine; 933745-86-9; 5-Br-4-Me-Pyrimidine-2-COOH
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Methyl-2-Pyrimidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.