Description

5-Bromo-2-Chloropyrimidine-4-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its reactive halogen and carboxylic acid functional groups, enabling precise molecular construction for complex target compounds. This intermediate is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for advanced organic electronic materials and metal-organic frameworks (MOFs) due to its functionalized aromatic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Item	Detail
Product Name	5-Bromo-2-Chloropyrimidine-4-Carboxylic Acid
CAS No.	933739-55-0
Molecular Formula	C5H2BrClN2O2
Molecular Weight	237.44 g/mol
Synonyms	5-Bromo-2-chloro-4-pyrimidinecarboxylic acid; 2-Chloro-5-bromopyrimidine-4-carboxylic acid; 4-Pyrimidinecarboxylic acid, 5-bromo-2-chloro-; 5-Bromo-2-chloropyrimidine-4-carboxylic acid; 933739-55-0; 5-Br-2-Cl-Pym-4-COOH
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloropyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.