Description

4,6-Dichloro-2-(Aminomethyl)Pyrimidine is a versatile and high-value heterocyclic building block, primarily used in advanced organic synthesis. Its core value proposition lies in its bifunctional reactivity, offering both a halogenated pyrimidine core and a primary amine side chain for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for the synthesis of active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its pyrimidine scaffold.
• Chemical Research & Development: Serves as a versatile precursor in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Ligand and Catalyst Development: The aminomethyl group can be functionalized to create novel ligands for metal catalysis or organocatalysts.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials with tailored properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Product Name	4,6-Dichloro-2-(Aminomethyl)Pyrimidine
CAS No.	933720-62-8
Molecular Formula	C5H5Cl2N3
Molecular Weight	178.02 g/mol
Synonyms	2-(Aminomethyl)-4,6-dichloropyrimidine; 4,6-Dichloro-2-pyrimidinemethanamine; (4,6-Dichloropyrimidin-2-yl)methanamine; 2-Aminomethyl-4,6-dichloropyrimidine; 4,6-Dichloro-2-(aminomethyl)pyrimidine; 933720-62-8; 4,6-Dichloro-2-pyrimidinylmethylamine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-(Aminomethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.