Description

1-(4-Fluorobenzyl)Pyrrolidine-3-Carboxylicacid is a high-purity fluorinated pyrrolidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which combines a fluorinated aromatic moiety with a functionalized pyrrolidine ring, enabling precise modifications in complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Building block for developing new generation herbicides, fungicides, and plant growth regulators.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics & Bioisosteres: The fluorobenzyl-pyrrolidine motif is valuable for designing peptide mimics and bioisosteric replacements in drug discovery.
• Chemical Biology Probes: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Intermediate for synthesizing specialty polymers and advanced organic materials with tailored properties.

Basic Information

Product Name	1-(4-Fluorobenzyl)Pyrrolidine-3-Carboxylicacid
CAS No.	933709-28-5
Molecular Formula	C12H14FNO2
Molecular Weight	223.25 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]-3-pyrrolidinecarboxylic acid; 3-Pyrrolidinecarboxylic acid, 1-[(4-fluorophenyl)methyl]-; 1-(4-Fluorobenzyl)pyrrolidine-3-carboxylic acid; 1-(4-Fluorobenzyl)-3-pyrrolidinecarboxylic acid; 1-(4-Fluorobenzyl)pyrrolidine-3-carboxylate; 933709-28-5; 1-(4-Fluorobenzyl)proline derivative
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)Pyrrolidine-3-Carboxylicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.