Description

1-(4-Methylpyrimidin-2-yl)methanamine dihydrochloride is a high-purity chemical building block and intermediate of significant importance in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other biological pathways where the pyrimidine scaffold is relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides that incorporate functionalized pyrimidine structures.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes, linkers, or tags used in studying biological systems and protein interactions.
• Material Science: Potential monomer or precursor for creating specialty polymers, ligands for catalysts, or organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	1-(4-Methylpyrimidin-2-yl)methanamine dihydrochloride
CAS No.	933682-85-0
Molecular Formula	C6H10N3 • 2HCl
Molecular Weight	212.09 g/mol (free base: 123.16 g/mol)
Synonyms	2-(Aminomethyl)-4-methylpyrimidine dihydrochloride; (4-Methyl-2-pyrimidinyl)methanamine dihydrochloride; 1-(4-Methyl-2-pyrimidinyl)methanamine hydrochloride (1:2); 4-Methyl-2-pyrimidinemethanamine dihydrochloride; 2-(Aminomethyl)-4-methylpyrimidine, 2HCl; 933682-85-0; 1-(4-Methylpyrimidin-2-yl)methanamine 2HCl
EINECS	Contact for details

Quality Control

Our 1-(4-Methylpyrimidin-2-yl)methanamine dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.