Description

2-(3,5-Bis-Trifluoromethyl-Phenoxymethyl)-Oxirane is a specialized fluorinated oxirane derivative, a high-value intermediate prized for its unique trifluoromethylated aromatic structure. This compound matters for its role in introducing fluorinated aromatic ether functionalities, which are critical for modifying the physical, chemical, and biological properties of advanced materials and active pharmaceutical ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced polymer industries seeking to enhance product performance through strategic fluorination.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting CNS disorders and oncology, where the trifluoromethyl group can improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides, where the fluorinated aromatic moiety contributes to enhanced efficacy and environmental persistence profiles.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers, coatings, and resins with desired properties like chemical resistance, low surface energy, and thermal stability.
• Liquid Crystal & OLED Materials: Incorporated into the molecular structure of fluorinated liquid crystals and organic light-emitting diode (OLED) materials to fine-tune electronic properties and improve device performance.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2-(3,5-Bis-Trifluoromethyl-Phenoxymethyl)-Oxirane
CAS No.	933673-35-9
Molecular Formula	C12H8F6O2
Molecular Weight	298.18 g/mol
Synonyms	2-[(3,5-Bis(trifluoromethyl)phenoxy)methyl]oxirane; 3,5-Bis(trifluoromethyl)phenyl glycidyl ether; Glycidyl 3,5-bis(trifluoromethyl)phenyl ether; 1,2-Epoxy-3-((3,5-bis(trifluoromethyl)phenoxy))propane; Oxirane, 2-[[[3,5-bis(trifluoromethyl)phenyl]oxy]methyl]-; 933673-35-9; α-(3,5-Bis(trifluoromethyl)phenoxy)methyl)oxirane
EINECS	Contact for details

Quality Control

Our 2-(3,5-Bis-Trifluoromethyl-Phenoxymethyl)-Oxirane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent lot-to-lot quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.