Description

2-Methyl-5-Trifluoromethylsulfanyl-Phenylamine is a specialized aromatic amine derivative featuring a trifluoromethylthio (-SCF₃) substituent, a functional group of significant interest in modern synthetic chemistry. This compound matters as a high-value pharmaceutical intermediate and agrochemical building block, enabling the introduction of lipophilic and metabolically stable motifs into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, crop protection, and advanced materials sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the -SCF₃ group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fluorine Chemistry: Valuable substrate for further functionalization in organofluorine chemistry, exploring novel reaction pathways involving the -SCF₃ moiety.

Basic Information

Product Name	2-Methyl-5-Trifluoromethylsulfanyl-Phenylamine
CAS No.	933673-21-3
Molecular Formula	C₈H₈F₃NS
Molecular Weight	207.22 g/mol
Synonyms	5-(Trifluoromethylthio)-o-toluidine; 2-Methyl-5-(trifluoromethylthio)aniline; 2-Methyl-5-(trifluoromethylsulfanyl)benzenamine; 2-Amino-4-methylphenyl trifluoromethyl sulfide; 2-Methyl-5-(trifluoromethylsulfanyl)phenylamine; Benzenamine, 2-methyl-5-[(trifluoromethyl)thio]-; 2-Methyl-5-(trifluoromethylthio)aniline
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-Trifluoromethylsulfanyl-Phenylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.