Description

7-(4-Chlorophenyl)-4,7-Dihydro[1,2,4]Triazolo[1,5-A]Pyrimidine-5-Carboxylic Acid is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, especially for creating candidates with triazolopyrimidine cores. The compound is supplied with a CAS Number of 933216-52-5.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery programs.
• Agrochemical Development: Used in research for creating new fungicides or herbicides, leveraging the biological activity of the triazolopyrimidine moiety.
• Chemical Biology Probe Synthesis: Employed in the development of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized, non-commercial compounds.

Basic Information

Product Name	7-(4-Chlorophenyl)-4,7-Dihydro[1,2,4]Triazolo[1,5-A]Pyrimidine-5-Carboxylic Acid
CAS No.	933216-52-5
Molecular Formula	C13H9ClN4O2
Molecular Weight	288.69 g/mol
Synonyms	7-(4-Chlorophenyl)-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid; 7-(p-Chlorophenyl)-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid; [1,2,4]Triazolo[1,5-a]pyrimidine-5-carboxylic acid, 7-(4-chlorophenyl)-4,7-dihydro-; 933216-52-5; 7-(4-Chlorophenyl)-4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidine-5-carboxylic acid; Triazolopyrimidine-5-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 7-(4-Chlorophenyl)-4,7-Dihydro[1,2,4]Triazolo[1,5-A]Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We can support development with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be stored away from light. Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.