Description

3-Amino-2-Methyl-5,6,7,8,9,10-Hexahydrocycloocta[4,5]Thieno[2,3-D]Pyrimidin-4(3H)-One is a high-purity, complex heterocyclic compound that serves as a critical advanced intermediate in modern pharmaceutical research and development. Its unique fused-ring structure, incorporating pyrimidine and thiophene motifs, makes it a valuable scaffold for medicinal chemistry, particularly in the design of novel kinase inhibitors and other targeted therapeutics. This compound is essential for research institutions and pharmaceutical companies engaged in the synthesis and optimization of new chemical entities for preclinical studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for oncology and central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Kinase Inhibitor Development: Its structural features are conducive to designing molecules that modulate kinase activity, a major focus in cancer therapy.
• Chemical Biology Probes: Employed in the development of tool compounds to study specific biological pathways and protein functions.
• Process Chemistry & Scale-Up: Serves as an intermediate for process research and development (PR&D) teams working on route optimization for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and intermediate supply.

Basic Information

Product Name	3-Amino-2-Methyl-5,6,7,8,9,10-Hexahydrocycloocta[4,5]Thieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	932929-14-1
Molecular Formula	C₁₃H₁₇N₃OS
Molecular Weight	263.36 g/mol
Synonyms	3-Amino-2-methyl-5,6,7,8,9,10-hexahydrocycloocta[4,5]thieno[2,3-d]pyrimidin-4-one; 2-Methyl-3-amino-4,5,6,7,8,9-hexahydrocycloocta[4,5]thieno[2,3-d]pyrimidin-4(3H)-one; Cycloocta[4,5]thieno[2,3-d]pyrimidin-4(3H)-one, 3-amino-5,6,7,8,9,10-hexahydro-2-methyl-; CAS 932929-14-1
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Methyl-5,6,7,8,9,10-Hexahydrocycloocta[4,5]Thieno[2,3-D]Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.