Description

1-[5-Methyl-7-(3-Phenoxyphenyl)-4,7-Dihydro[1,2,4]Triazolo[1,5-A]Pyrimidin-6-Yl]Ethanone is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrimidine class of heterocyclic compounds. Its complex molecular architecture makes it a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries seeking to develop new small-molecule therapies.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) disease research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme inhibition and biological pathway modulation.
• Process Chemistry & Scale-Up: Supplied in development and pilot-scale quantities for route optimization and cGMP manufacturing campaigns.
• Reference Standard: Provides a high-purity benchmark for analytical method development, validation, and quality control in API production.
• Custom Synthesis Building Block: Utilized by fine chemical manufacturers for the bespoke synthesis of complex molecules for client-specific projects.

Basic Information

Product Name	1-[5-Methyl-7-(3-Phenoxyphenyl)-4,7-Dihydro[1,2,4]Triazolo[1,5-A]Pyrimidin-6-Yl]Ethanone
CAS No.	932255-28-2
Molecular Formula	C21H18N4O2
Molecular Weight	358.40 g/mol
Synonyms	6-Acetyl-5-methyl-7-(3-phenoxyphenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine; Ethanone, 1-[5-methyl-7-(3-phenoxyphenyl)-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]-; 1-(5-Methyl-7-(3-phenoxyphenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)ethan-1-one; [1,2,4]Triazolo[1,5-a]pyrimidine derivative (CAS 932255-28-2); 5-Methyl-7-(3-phenoxyphenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl methyl ketone
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems (ISO 9001) to ensure batch-to-batch consistency and reliability. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods (HPLC, GC, NMR). We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.