Description

Pyrido[3,4-E][1,2,4]Triazolo[1,5-A]Pyrimidin-6(7H)-One (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate with the CAS number 932233-33-5. This heterocyclic compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of investigational new drugs and targeted therapies.
• Oncology Research: Serves as a core scaffold for developing kinase inhibitors and other anti-cancer agents.
• CNS Drug Discovery: Used in constructing molecules for neurological and psychiatric disorder treatments.
• Chemical Biology: Employed as a probe or tool compound for studying enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for API manufacturing under cGMP conditions.
• Contract Research & Development (CRO/CMO): Supplied to partners specializing in custom synthesis and early-stage development.

Basic Information

Product Name	Pyrido[3,4-E][1,2,4]Triazolo[1,5-A]Pyrimidin-6(7H)-One (Saltdata: Free)
CAS No.	932233-33-5
Molecular Formula	C9H5N5O
Molecular Weight	199.17 g/mol
Synonyms	Pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-6(7H)-one; 7H-Pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-6-one; 932233-33-5; Free base of Pyrido-triazolo-pyrimidinone; PTAP intermediate; 1,2,4-Triazolo[1,5-a]pyrido[3,4-e]pyrimidin-6(7H)-one
EINECS	Contact for details

Quality Control

Our Pyrido[3,4-E][1,2,4]Triazolo[1,5-A]Pyrimidin-6(7H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term stability is required. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.