Description

Pyrido[4,3-D]Pyrimidine-6(5H)-Carboxylic Acid, 7,8-Dihydro-2-(4-Morpholinyl)-, 1,1-Dimethylethyl Ester is a high-value, heterocyclic organic building block featuring a fused pyrido-pyrimidine core substituted with a morpholine ring and a tert-butyl ester group. This compound is critical for medicinal chemistry research and development, serving as a versatile intermediate for constructing novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers focused on developing kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a starting material for synthesizing tool compounds to study specific biological pathways and target validation.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of complex, high-purity active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Pyrido[4,3-D]Pyrimidine-6(5H)-Carboxylic Acid, 7,8-Dihydro-2-(4-Morpholinyl)-, 1,1-Dimethylethyl Ester
CAS No.	931335-89-6
Molecular Formula	C16H23N3O3
Molecular Weight	305.37 g/mol
Synonyms	tert-Butyl 7,8-dihydro-2-(morpholin-4-yl)pyrido[4,3-d]pyrimidine-6(5H)-carboxylate; 931335-89-6; 2-Morpholin-4-yl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-6-carboxylic acid tert-butyl ester; 7,8-Dihydro-2-(4-morpholinyl)pyrido[4,3-d]pyrimidine-6(5H)-carboxylic acid 1,1-dimethylethyl ester; Pyrido[4,3-d]pyrimidine-6(5H)-carboxylic acid, 7,8-dihydro-2-(4-morpholinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Pyrido[4,3-D]Pyrimidine-6(5H)-Carboxylic Acid, 7,8-Dihydro-2-(4-Morpholinyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.