Description

(1S)-2,2,2-Trifluoro-1-(4-Fluorophenyl)Ethylamine is a high-purity chiral amine building block of significant importance in modern synthetic chemistry. Its core value lies in its unique trifluoromethyl and fluorophenyl groups, which are critical for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries who require advanced intermediates for the synthesis of novel active ingredients.

Application

• As a key chiral intermediate in the research and development of new pharmaceutical candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Utilized in the synthesis of advanced agrochemicals, where the fluorine atoms contribute to enhanced herbicidal or insecticidal activity and environmental stability.
• Serves as a crucial building block for creating novel ligands and catalysts used in asymmetric synthesis.
• Employed in the development of positron emission tomography (PET) tracers and other diagnostic agents due to the presence of fluorine atoms.
• Used in material science research for the synthesis of specialty polymers and liquid crystals with unique electronic properties.
• Acts as a precursor for the synthesis of more complex fluorinated compounds in advanced organic chemistry research.

Basic Information

Product Name	(1S)-2,2,2-Trifluoro-1-(4-Fluorophenyl)Ethylamine
CAS No.	929804-89-7
Molecular Formula	C8H7F4N
Molecular Weight	193.14 g/mol
Synonyms	(S)-1-(4-Fluorophenyl)-2,2,2-trifluoroethylamine; (1S)-1-(4-Fluorophenyl)-2,2,2-trifluoroethanamine; (S)-α-(Trifluoromethyl)-4-fluorobenzeneethanamine; (S)-1-(4-Fluorophenyl)-2,2,2-trifluoroethylamine; (S)-4-Fluoro-α-(trifluoromethyl)benzylamine; (S)-(-)-1-(4-Fluorophenyl)-2,2,2-trifluoroethylamine; (S)-Trifluoro(4-fluorophenyl)ethylamine
EINECS	Contact for details

Quality Control

Our (1S)-2,2,2-Trifluoro-1-(4-Fluorophenyl)Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with high-purity standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.