Description

(S)-2,2,2-Trifluoro-1-(o-Tolyl)Ethanamine Hcl is a high-purity chiral amine building block, specifically the hydrochloride salt of the (S)-enantiomer. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents, particularly those targeting central nervous system disorders. It is essential for research and development chemists and process scale-up teams in the pharmaceutical and fine chemical industries who require enantiomerically pure intermediates for drug discovery and manufacturing.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), especially for neurological and psychiatric therapeutics.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to create enantiomerically pure compounds.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing novel molecular libraries in drug discovery programs.
• Agrochemical Development: Employed in the synthesis of advanced, chiral crop protection agents and pesticides.
• Ligand and Catalyst Preparation: Useful for the development of chiral ligands and organocatalysts used in fine chemical synthesis.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(S)-2,2,2-Trifluoro-1-(o-Tolyl)Ethanamine Hydrochloride
CAS No.	929642-60-4
Molecular Formula	C9H11ClF3N
Molecular Weight	225.64 g/mol
Synonyms	(S)-2,2,2-Trifluoro-1-(2-methylphenyl)ethanamine hydrochloride; (S)-α-Methyl-2-(trifluoromethyl)benzylamine hydrochloride; (S)-1-(2-Methylphenyl)-2,2,2-trifluoroethanamine HCl; (S)-o-Tolyl-2,2,2-trifluoroethylamine hydrochloride; (S)-TFM Benzhydrylamine HCl; (S)-2,2,2-Trifluoro-1-(2-tolyl)ethylamine hydrochloride; (S)-1-(2-Methylphenyl)-2,2,2-trifluoroethan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2,2,2-Trifluoro-1-(o-Tolyl)Ethanamine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.