Description

6-Bromo-2-(Trifluoromethyl)Quinazolin-4-Amine is a high-value, multi-functional heterocyclic building block featuring a bromine atom and a trifluoromethyl group on a quinazoline core. This compound is prized for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the agrochemical and life sciences industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and pesticides, leveraging the biological activity of the quinazoline scaffold.
• Material Science Precursor: Serves as a building block for advanced organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and biochemical probe development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	6-Bromo-2-(Trifluoromethyl)Quinazolin-4-Amine
CAS No.	929379-35-1
Molecular Formula	C9H5BrF3N3
Molecular Weight	292.06 g/mol
Synonyms	4-Amino-6-bromo-2-(trifluoromethyl)quinazoline; 6-Bromo-2-(trifluoromethyl)-4-quinazolinamine; 6-Bromo-2-trifluoromethylquinazolin-4-ylamine; Quinazolin-4-amine, 6-bromo-2-(trifluoromethyl)-; 929379-35-1
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(Trifluoromethyl)Quinazolin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced intermediates intended for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.