Description

n-(2,2,2-Trifluoroethyl)Benzenamine Hydrochloride is a specialized organofluorine compound, serving as a crucial building block in advanced chemical synthesis. Its value lies in the unique reactivity imparted by the trifluoroethylamine moiety, which is essential for modulating the biological activity and physicochemical properties of target molecules. This high-purity intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers developing novel active ingredients, particularly in agrochemical and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal complexes.
• Material Science Research: Intermediate for synthesizing fluorinated polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	n-(2,2,2-Trifluoroethyl)Benzenamine Hydrochloride
CAS No.	929286-62-4
Molecular Formula	C8H9ClF3N
Molecular Weight	211.61 g/mol
Synonyms	N-(2,2,2-Trifluoroethyl)aniline hydrochloride; Benzenamine, N-(2,2,2-trifluoroethyl)-, hydrochloride; 2,2,2-Trifluoro-N-phenylethylamine hydrochloride; α,α,α-Trifluoro-N-phenylethylamine hydrochloride; N-Phenyl-2,2,2-trifluoroethylamine hydrochloride; 929286-62-4; (2,2,2-Trifluoroethyl)phenylamine hydrochloride
EINECS	Contact for details

Quality Control

Our n-(2,2,2-Trifluoroethyl)Benzenamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.