Description

4-Isothiocyanato-2,6-Dimethylpyrimidine is a versatile heterocyclic building block characterized by its reactive isothiocyanate functional group. This compound is of significant value in synthetic organic and medicinal chemistry for the construction of complex molecular architectures. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for applications in drug discovery and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging its pyrimidine core.
• Chemical Biology Probe Development: The reactive isothiocyanate group allows for covalent modification of proteins and other biomolecules, useful in activity-based protein profiling (ABPP).
• Material Science: Serves as a monomer or cross-linking agent in the preparation of specialty polymers and functional materials.
• Organic Synthesis Building Block: Employed in cycloaddition reactions and as a precursor for other functionalized pyrimidine derivatives.

Basic Information

Product Name	4-Isothiocyanato-2,6-Dimethylpyrimidine
CAS No.	928714-57-2
Molecular Formula	C7H7N3S
Molecular Weight	165.21 g/mol
Synonyms	2,6-Dimethyl-4-isothiocyanatopyrimidine; 4-Isothiocyanato-2,6-lutidine; 2,6-Dimethylpyrimidine-4-isothiocyanate; 4-Isothiocyanato-2,6-dimethylpyrimidine; 928714-57-2; 4-Isothiocyanato-2,6-dimethyl-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Isothiocyanato-2,6-Dimethylpyrimidine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.