Description

2-Oxo-2,3,4,5-Tetrahydro-1H-1-Benzazepine-7-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation reagent, enabling the efficient introduction of the sulfonamide functional group into complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of benzazepine-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the sulfonamide moiety is required for biological activity.
• Chemical Research & Development: Serves as a versatile reagent for constructing sulfonamide libraries in medicinal chemistry for high-throughput screening (HTS).
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, dyes, and functional materials requiring specific sulfonylation.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for commercial manufacturing of target molecules.

Basic Information

Product Name	2-Oxo-2,3,4,5-Tetrahydro-1H-1-Benzazepine-7-Sulfonyl Chloride
CAS No.	927869-56-5
Molecular Formula	C10H10ClNO3S
Molecular Weight	259.71 g/mol
Synonyms	7-(Chlorosulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one; 1H-1-Benzazepine-7-sulfonyl chloride, 2,3,4,5-tetrahydro-2-oxo-; 2-Oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-7-sulfonyl chloride; Tetrahydrobenzazepine sulfonyl chloride; 927869-56-5; 7-Chlorosulfonyl-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
EINECS	Contact for details

Quality Control

Our 2-Oxo-2,3,4,5-Tetrahydro-1H-1-Benzazepine-7-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.