Description

5-Bromo-2-[(4-Methoxycarbonyl)Phenoxy]Pyrimidine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrimidine core functionalized with bromo and phenoxy ester groups. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily needed by R&D laboratories and manufacturing facilities in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, especially kinase inhibitors and other targeted small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to the reactive bromine substituent.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and liquid crystals.

Basic Information

Product Name	5-Bromo-2-[(4-Methoxycarbonyl)Phenoxy]Pyrimidine
CAS No.	926304-76-9
Molecular Formula	C13H9BrN2O3
Molecular Weight	321.13 g/mol
Synonyms	5-Bromo-2-[(4-methoxycarbonyl)phenoxy]pyrimidine; Methyl 4-((5-bromopyrimidin-2-yl)oxy)benzoate; 2-(4-Carbomethoxyphenoxy)-5-bromopyrimidine; 5-Bromo-2-(4-methoxycarbonylphenoxy)pyrimidine; 5-Bromo-2-(4-(methoxycarbonyl)phenoxy)pyrimidine; 926304-76-9; Methyl 4-[(5-bromopyrimidin-2-yl)oxy]benzoate
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-[(4-Methoxycarbonyl)Phenoxy]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.