Description

1-[3-(Difluoromethoxy)Phenyl]Ethan-1-Amine is a specialized aromatic amine building block featuring a difluoromethoxy substituent. This compound is valued for its role as a key intermediate in the synthesis of advanced pharmaceutical and agrochemical agents, where its unique fluorine-containing moiety can enhance metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the difluoromethoxy group can improve pesticidal activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials that require fluorine-modified aromatic components.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and fluorescent tags used in biochemical and diagnostic research.

Basic Information

Product Name	1-[3-(Difluoromethoxy)Phenyl]Ethan-1-Amine
CAS No.	926263-64-1
Molecular Formula	C9H11F2NO
Molecular Weight	187.19 g/mol
Synonyms	1-[3-(Difluoromethoxy)phenyl]ethanamine; α-Methyl-3-(difluoromethoxy)benzylamine; 3-(Difluoromethoxy)-α-methylbenzylamine; 1-(3-(Difluoromethoxy)phenyl)ethanamine; (RS)-1-[3-(Difluoromethoxy)phenyl]ethylamine; 1-(3-(Difluoromethoxyphenyl))ethylamine; 3-(Difluoromethoxy)phenethylamine, α-methyl-
EINECS	Contact for details

Quality Control

Our production of 1-[3-(Difluoromethoxy)Phenyl]Ethan-1-Amine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, and we support compliance with relevant regulatory frameworks for pharmaceutical and agrochemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.