Description

n-(3-Amino-4-Fluorophenyl)Cyclopropanecarboxamide is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopropane-carboxamide scaffold. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted kinase inhibitors and other small-molecule therapeutics. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry for oncology, anti-inflammatory, and central nervous system (CNS) applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Drug Discovery & Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of API manufacturing processes.
• Oncology Research: Employed in the development of compounds targeting specific cancer pathways.
• Agrochemical Intermediate: Potential use in the synthesis of advanced crop protection agents with novel modes of action.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	n-(3-Amino-4-Fluorophenyl)Cyclopropanecarboxamide
CAS No.	926210-86-8
Molecular Formula	C10H11FN2O
Molecular Weight	194.21 g/mol
Synonyms	N-(3-Amino-4-fluorophenyl)cyclopropanecarboxamide; 3-Amino-4-fluoro-N-cyclopropylbenzamide; Cyclopropanecarboxamide, N-(3-amino-4-fluorophenyl)-; 926210-86-8; 4-Fluoro-3-aminophenyl cyclopropyl ketone amide; 1-(3-Amino-4-fluorophenylamino)cyclopropanecarboxylic acid amide; 3-Amino-4-fluorobenzenecyclopropanecarboxamide
EINECS	Contact for details

Quality Control

Our n-(3-Amino-4-Fluorophenyl)Cyclopropanecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.