Description

1-{4-Methyl-2-[(4,6,8-Trimethylquinazolin-2-Yl)-Amino]Pyrimidin-5-Yl}Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of sophisticated active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinazoline and pyrimidine-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Kinase Inhibitor Development: Serves as a core scaffold for the research and development of potential kinase inhibitors.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules for biological screening.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	1-{4-Methyl-2-[(4,6,8-Trimethylquinazolin-2-Yl)-Amino]Pyrimidin-5-Yl}Ethanone
CAS No.	925645-95-0
Molecular Formula	C19H19N5O
Molecular Weight	333.39 g/mol
Synonyms	1-[4-Methyl-2-[[(4,6,8-trimethyl-2-quinazolinyl)amino]-5-pyrimidinyl]ethanone; 1-(4-Methyl-2-((4,6,8-trimethylquinazolin-2-yl)amino)pyrimidin-5-yl)ethan-1-one; 2-((4,6,8-Trimethylquinazolin-2-yl)amino)-4-methylpyrimidin-5-yl methyl ketone; CAS 925645-95-0; Ethanone, 1-[4-methyl-2-[[(4,6,8-trimethyl-2-quinazolinyl)amino]-5-pyrimidinyl]-
EINECS	Contact for details

Quality Control

Our 1-{4-Methyl-2-[(4,6,8-Trimethylquinazolin-2-Yl)-Amino]Pyrimidin-5-Yl}Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) documenting purity, related substances, and other critical parameters are available upon request to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.