Description

2-(2-Aminopyrimidin-4-Yl)-4-Bromophenol is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic phenolic structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is essential for medicinal chemistry teams in pharmaceutical R&D, agrochemical innovators, and specialty chemical manufacturers seeking to develop novel therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry R&D: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides that leverage its pyrimidine core.
• Biochemical Research: Employed as a reference standard or probe molecule in biochemical assays and enzymatic studies.
• Fine Chemical Production: Acts as a building block for creating complex, high-value specialty chemicals with specific electronic or steric properties.
• Material Science: Potential monomer or additive in the development of advanced polymers and functional materials.

Basic Information

Product Name	2-(2-Aminopyrimidin-4-Yl)-4-Bromophenol
CAS No.	925003-46-9
Molecular Formula	C10H8BrN3O
Molecular Weight	266.10 g/mol
Synonyms	4-Bromo-2-(2-aminopyrimidin-4-yl)phenol; 2-(2-Amino-4-pyrimidinyl)-4-bromophenol; 4-Bromo-2-(2-pyrimidinamin-4-yl)phenol; Phenol, 4-bromo-2-(2-amino-4-pyrimidinyl)-; 925003-46-9; 2-(2-Aminopyrimidin-4-yl)-4-bromophenol; 4-Bromo-2-(2-aminopyrimidin-4-yl)phenol
EINECS	Contact for details

Quality Control

Our 2-(2-Aminopyrimidin-4-Yl)-4-Bromophenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques such as HPLC, NMR, and mass spectrometry. We are committed to meeting the stringent requirements of pharmaceutical development and other high-precision industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.