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5-Allyl-6-Methyl-2-[(4,6,7-Trimethylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One CAS NO 924874-35-1
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CAS No.:924874-35-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
5-Allyl-6-Methyl-2-[(4,6,7-Trimethylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel therapeutic agents. This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold for targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing kinase inhibitors and other small-molecule drugs.
Application
- Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors and other targeted small-molecule therapeutics.
- Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
- Biochemical Research: Serves as a reference standard or probe compound in enzymatic assays and biological target validation.
- Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex molecules for academic and industrial research.
- Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of active pharmaceutical ingredients (APIs) under development.
Basic Information
| Product Name | 5-Allyl-6-Methyl-2-[(4,6,7-Trimethylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One |
| CAS No. | 924874-35-1 |
| Molecular Formula | C20H22N6O |
| Molecular Weight | 362.43 g/mol |
| Synonyms | 5-Allyl-6-methyl-2-((4,6,7-trimethylquinazolin-2-yl)amino)pyrimidin-4(3H)-one; 2-((5-Allyl-6-methyl-4-oxo-3,4-dihydropyrimidin-2-yl)amino)-4,6,7-trimethylquinazoline; 924874-35-1; 5-Allyl-6-methyl-2-[(4,6,7-trimethyl-2-quinazolinyl)amino]-4(3H)-pyrimidinone; 4(3H)-Pyrimidinone, 5-allyl-6-methyl-2-[(4,6,7-trimethyl-2-quinazolinyl)amino]- |
| EINECS | Contact for details |
Quality Control
Our 5-Allyl-6-Methyl-2-[(4,6,7-Trimethylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, it should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the primary container.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.




