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5-Allyl-6-Methyl-2-[(4,6,7-Trimethylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One CAS NO 924874-35-1


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CAS No.:924874-35-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Allyl-6-Methyl-2-[(4,6,7-Trimethylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel therapeutic agents. This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold for targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing kinase inhibitors and other small-molecule drugs.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors and other targeted small-molecule therapeutics.
  • Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
  • Biochemical Research: Serves as a reference standard or probe compound in enzymatic assays and biological target validation.
  • Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex molecules for academic and industrial research.
  • Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of active pharmaceutical ingredients (APIs) under development.

Basic Information

Product Name 5-Allyl-6-Methyl-2-[(4,6,7-Trimethylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One
CAS No. 924874-35-1
Molecular Formula C20H22N6O
Molecular Weight 362.43 g/mol
Synonyms 5-Allyl-6-methyl-2-((4,6,7-trimethylquinazolin-2-yl)amino)pyrimidin-4(3H)-one; 2-((5-Allyl-6-methyl-4-oxo-3,4-dihydropyrimidin-2-yl)amino)-4,6,7-trimethylquinazoline; 924874-35-1; 5-Allyl-6-methyl-2-[(4,6,7-trimethyl-2-quinazolinyl)amino]-4(3H)-pyrimidinone; 4(3H)-Pyrimidinone, 5-allyl-6-methyl-2-[(4,6,7-trimethyl-2-quinazolinyl)amino]-
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Quality Control

Our 5-Allyl-6-Methyl-2-[(4,6,7-Trimethylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, it should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the primary container.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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