Description

7-Methyl-2-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its fused triazolopyrimidine heterocyclic core and carboxylic acid functionality. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the biological activity of the triazolopyrimidine structure.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study biological processes and identify new drug targets.
• Material Science Research: Potential precursor for the synthesis of specialized ligands or functional molecules used in advanced materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations conducting custom synthesis and process development for clients.

Basic Information

Product Name	7-Methyl-2-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylic Acid
CAS No.	924846-75-3
Molecular Formula	C9H5F3N4O2
Molecular Weight	258.16 g/mol
Synonyms	7-Methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid; 7-Methyl-2-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid; 924846-75-3; 6-Carboxy-7-methyl-2-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyrimidine; [1,2,4]Triazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-methyl-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 7-Methyl-2-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key specifications such as assay (HPLC), related substances, and residual solvents. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.