Description

6-Mercapto-1-(4-Methylphenyl)-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This heterocyclic compound is valued for its role as a critical building block in the synthesis of novel therapeutic agents, particularly in kinase inhibitor development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in producing targeted, small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a reference standard or active scaffold in structure-activity relationship (SAR) studies and high-throughput screening.
• API Development: Serves as a core structural component in the development of new Active Pharmaceutical Ingredients (APIs) targeting specific enzymatic pathways.
• Academic Research: Employed in university and institutional labs for medicinal chemistry projects and the exploration of new heterocyclic chemistry.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	6-Mercapto-1-(4-Methylphenyl)-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One
CAS No.	923784-01-4
Molecular Formula	C₁₂H₁₀N₄OS
Molecular Weight	258.30 g/mol
Synonyms	6-Mercapto-1-p-tolyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 1-(4-Methylphenyl)-6-mercapto-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 6-Thioxo-1-(p-tolyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 923784-01-4; CAS 923784-01-4
EINECS	Contact for details

Quality Control

Our 6-Mercapto-1-(4-Methylphenyl)-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of global pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.