Description

5-Chloro-3-iodopyrazolo[1,5-a]pyrimidine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring both halogen substituents, makes it a versatile intermediate for constructing complex molecular architectures through selective cross-coupling and functionalization reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive scaffold.
• Material Science: Acts as a building block for creating specialized organic electronic materials and ligands for catalysis.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Cross-Coupling Reactions: The iodine and chlorine atoms provide distinct sites for sequential Suzuki, Sonogashira, or Buchwald-Hartwig amination reactions.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	5-Chloro-3-iodopyrazolo[1,5-a]pyrimidine
CAS No.	923595-58-8
Molecular Formula	C6H2ClIN3
Molecular Weight	293.46 g/mol
Synonyms	5-Chloro-3-iodopyrazolo[1,5-a]pyrimidine; 5-Chloro-3-iodo-1H-pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine, 5-chloro-3-iodo-; 3-Iodo-5-chloropyrazolo[1,5-a]pyrimidine; 923595-58-8; 5-Chloro-3-iodo-7-azaindazole (common name); 5-Chloro-3-iodo-pyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-iodopyrazolo[1,5-a]pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder/crystals
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.